Invitation to the presentation of Cosmo Pharmaceuticals’ year-end results 2012 on 28 March 2013 Montag, 11. März 2013 - 10:00

Dear Madam or Sir,

Cosmo Pharmaceuticals S.p.A. (SIX:COPN), a specialty pharma company that aims to become a global leader in the market of optimized therapies for selected Gastrointestinal and Skin Disorders, cordially invites you to the year-end 2012 analyst and media presentation in Zurich.

Mauro Ajani, CEO, Luigi Moro, CSO, and Chris Tanner, CFO and Head of Investor Relations, will present the 2012 results and discuss the outlook for 2013.

The conference will be held in English.

Participation is also possible via conference call. The dial-in numbers are:

Continental Europe: +41 (0) 58 310 50 00

UK: +44 (0) 203 0595 862

USA: +1 613 570 56 13

The presentation will be available for download at www.cosmopharma.com at 7.00 am CET on 28 March 2013.

We kindly ask you to confirm your attendance by filling in and returning the enclosed registration form or by sending an email to Markus Germann, markus.germann@irfcom.ch, by 21 March 2013.

We look forward to welcoming you at the conference.

Yours sincerely,

Chris Tanner

CFO and Head of Investor Relations